|Minor league affiliations|
|Division||North Division (1985-1989)|
|Major league affiliations|
|Minor league titles|
|League titles||1 (1960)|
The Wytheville Cubs was the final name of the minor league baseball teams located in Wytheville, Virginia between 1948 and 1989. An affiliate of the Chicago Cubs from 1985 to 1989, the Wytheville Cubs were a member of the Rookie level Appalachian League. Previous Wytheville teams played as members of the Blue Ridge League (1948-1949) and Appalachian League (1953-1955, 1957-1965, 1967, 1969, 1971-1973).
The Wytheville Cubs finished with their best record in their first year, when they went 39-31, finishing third in the 1985 Appalachian League.
Previously, Wytheville was home of the Wytheville Braves (1971-1973), Wytheville Senators (1960, 1965, 1969), Wytheville Reds (1967), Wytheville A's (1964), Wytheville Twins (1961-1963), Wytheville Cardinals (1957-1959), Wytheville Statesman (1949, 1953-1955) and Wytheville Pioneers (1948). Wytheville was an affiliate of the Chicago Cubs (1985–1989), Atlanta Braves (1971-1973), Washington Senators II (1965, 1969), Cincinnati Reds (1967), Kansas City A's (1964), Minnesota Twins (1961-1963), Washington Senators I (1960), St. Louis Cardinals (1957-1959), Baltimore Orioles (1954), and St. Louis Browns (1953).
The 1960 Wytheville Senators captured the Appalachian League Championship.
Wytheville teams played at Withers Field. Constructed in 1948, the ballpark hosted all Wytheville minor league teams during its existence. The ballpark was repurposed in 1993 to become a public park, renamed Withers Park. Its grandstand and brick exterior are still in existence today within the park and a plaque recognizes the home plate location. The address is 300 North 4th Street, Wytheville, Virginia, 24382.
Year-by-year Cubs record
Notable franchise alumni
- Alex Arias (1987)
- Jeff Burroughs (1969) 2x MLB All-Star; 1974 AL Most Valuable Player
- Frank Castillo (1987)
- Matt Franco (1987-1988)
- Julio Gotay (1957)
- Jack Hamilton (1957)
- Pete Mackanin (1969)
- Charlie Manuel (1963) Manager: 2008 World Series Champion-Philadelphia Phillies
- Derrick May (1986)
- Tony Oliva 3x MLB All-Star; 1964 AL Rookie of the Year; 3x AL Batting Title (1964, 1965, 1971)
- Biff Pocoroba MLB All-Star
- Joe Rudi 3x MLB All-Star
- Ellie Rodríguez (1964) 2x MLB All-Star
- Reggie Smith 7x MLB All-Star
- Dave Tomlin (1967)
- Jerome Walton (1986) 1989 NL Rookie of the Year