The South Carolina Little Three (known as the South Carolina Little Four from 1946 to 1951) was an intercollegiate athletic conference that existed from 1946 to 1964. The conference's three main members, Newberry College, Presbyterian College, and Wofford College, were located in the state of South Carolina. All three teams now play in different leagues: Newberry in the South Atlantic (Division II), Presbyterian in the Big South (FCS), and Wofford in the SoCon (FCS). Erskine College was also a member from 1946 to 1951 when it dropped its football program. Erskine has announced that their football program is returning for the 2020 season. The College of Charleston was also a member of the South Carolina Little Five in basketball, now playing in the Colonial Athletic Association, but the post-season basketball tournament was always for the South Carolina Little Four and the College of Charleston was not invited.
- The following is an incomplete list of the membership of the South Carolina Little Four Conference.
|College of Charleston||Charleston, South Carolina||1770||Cougars||1946||1953||Colonial Athletic Association|
|Erskine College||Due West, South Carolina||1839||Flying Fleet||1946||1951 (football)
|Newberry College||Newberry, South Carolina||1856||Wolves||1946||1964||South Atlantic|
|Presbyterian College||Clinton, South Carolina||1851||Blue Hose||1946||1964||Big South|
|Wofford College||Spartanburg, South Carolina||1854||Terriers||1946||1964||Southern|
† = Qualified to the NAIA Men's Basketball Championships
- List of defunct college football conferences
- South Atlantic Conference
- Conference Carolinas
- Southern Conference
- Big South Conference
- Colonial Athletic Association
- South Carolina Little Three, College Football Data Warehouse, retrieved October 26, 2015.
- "Birds, Terriers on Top as State Cage Year Ends", Times and Democrat, Orangeburg, SC, p. 11, March 3, 1947
- "Carolina and Wofford Lead in Basketball", Greenville News, Greenville, SC, p. 6, March 1, 1948
- "Fleet to Play Lenoir-Rhyne For K.C. Bid", Greenville News, Greenville, SC, p. 8, February 28, 1949
- "Carolina Gains Laurels as Top State Quintet", Florence Morning News, Florence, SC, p. 8, March 1, 1950
- "PC Has State's Best Over-all Season Record", Florence Morning News, Florence, SC, p. 5, February 26, 1951
- "State Cagers Have 3 Games Left on Slate", Greenville News, Greenville, SC, p. 7, February 25, 1952
- "Furman Cops Big 4 Honors", Greenville News, Greenville, SC, p. 8, March 2, 1953