|Maintained by MassDOT|
|Length||60.69 mi (97.67 km)|
|South end||US 202 / Route 10 in Granby, CT|
| US 20 in Westfield|
I-90 / US 202 in Westfield
US 5 in Northampton and Bernardston
I-91 in Northampton, Hatfield, and Whately
Route 2 in Greenfield
|North end||NH 10 in Winchester, NH|
|Counties||Hampden, Hampshire, Franklin|
Massachusetts Route 10 is a 60.69-mile-long (97.67 km) north–south state highway that runs from the Connecticut state line at Southwick to the New Hampshire state line at Northfield. Originally part of New England Route 10 from 1922 to 1927, it continues to the south as Connecticut Route 10, and to the north as New Hampshire Route 10.
Route 10 crosses the border from Granby, Connecticut into Southwick, Massachusetts, overlapped with U.S. 202. It runs north through the Pioneer Valley towns of Southwick, Westfield, Southampton, Easthampton, Northampton, Hatfield, Whately, Deerfield, Greenfield, Bernardston, Gill, and Northfield. Route 10 has a long concurrency with U.S. 5 for about 25 miles (40 km) from Northampton to Bernardston, where it was sometimes called the "5 & 10 Highway". During this concurrency, it closely parallels Interstate 91, with five exits from Northampton to Deerfield, with close access at Route 2 in Greenfield and another exit, solely for Route 10, in Bernardston. It crosses the Connecticut River in Northfield before entering New Hampshire.
Route 10 is concurrent with seven other routes (US 5, US 20, US 202, and Massachusetts Routes 57, 9, 116, and 63) for 43 miles (69.20 km) of its nearly 61 miles (98.17 km) in the state with three points of triple concurrency, leaving less than a third of its length as the sole road designation.
An odd sight greeted motorists in Easthampton in July 2005: standard issue Alabama state highway signs with the number 10 in a map of that state, instead of the standard Massachusetts square. This odd "Alabama 10" signage came about when a contractor mistakenly applied the sample from a federal manual. The signs have since been replaced with the correct shields.
|Hampden||Southwick||0.0||0.0||US 202 south / Route 10 south – Salmon Brook||Continuation into Connecticut; Southern terminus of concurrency with US 202|
|1.9||3.1||Route 168 east – West Suffield, CT, Suffield, CT||Western terminus of Route 168|
|4.3||6.9||Route 57 west – Granville, New Marlborough||Southern terminus of concurrency with Route 57|
|4.9||7.9||Route 57 east – Feeding Hills, Springfield||Northern terminus of concurrency with Route 57|
|Westfield||9.6||15.4||US 20 east – Springfield, Palmer||Southern terminus of concurrency with US 20|
|9.9||15.9||US 20 west – Russell, Pittsfield||Northern terminus of concurrency with US 20|
|11.3||18.2||I-90 / Mass Pike – Boston, Albany, NY||Exit 41 on I-90 / Massachusetts Turnpike|
|14.3||23.0||US 202 north – Holyoke, Belchertown||Northern terminus of concurrency with US 202|
|Hampshire||Easthampton||21.8||35.1||Route 141 east – Holyoke||Western terminus of Route 141|
|Northampton||26.1||42.0||Route 9 west – Williamsburg, Pittsfield||Southern terminus of concurrency with Route 9|
|26.4||42.5||Route 9 east / US 5 south – Amherst, Worcester, Holyoke, Springfield||Northern terminus of concurrency with Route 9; southern terminus of concurrency with US 5|
|27.8||44.7||I-91 north – Greenfield, Brattleboro, VT||Exit 26 on I-91; northbound exit and southbound entrance|
|29.6||47.6||I-91 – Springfield, Brattleboro, VT||Exit 27 on I-91; northbound access via Elm Street|
|Hatfield||32.0||51.5||I-91 south – Holyoke, Springfield||Exit 30 on I-91|
|32.3||52.0||I-91 north – Greenfield, Brattleboro, VT||Exit 30 on I-91|
|Franklin||Whately||34.0||54.7||I-91 north – Greenfield, Brattleboro VT||Exit 32 on I-91; northbound entrance|
|34.7||55.8||I-91||Exit 32 on I-91; entrance from I-91 south|
|37.1||59.7||I-91 south – Holyoke, Springfield||Exit 35 on I-91; no exit from southbound|
|37.4||60.2||Route 116 south – Sunderland, Amherst||Southern terminus of concurrency with Route 116|
Route 116 north to I-91 north – Conway, Ashfield
|Northern terminus of concurrency with Route 116|
|Deerfield River||44.6||71.8||Deerfield River Bridge|
|Greenfield||46.0||74.0||Route 2A – Athol||Court Square, site of historic road marker|
Route 2 to I-91 – Boston, North Adams
|Bernardston||52.5||84.5||US 5 north – Brattleboro VT, White River Jct., VT||Northern terminus of concurrency with US 5|
|52.9||85.1||I-91 – Greenfield, Springfield, Brattleboro, VT, White River Jct., VT||Exit 50 on I-91|
|Gill||55.5||89.3||Route 142 north – Northfield, Vernon, VT||Southern terminus of Route 142|
|Connecticut River||56.8||91.4||Bennett's Meadow Bridge|
|Northfield||57.5||92.5||Route 63 south – Millers Falls, Amherst||Southern terminus of concurrency with Route 63|
|59.9||96.4||Route 63 north – Hinsdale, NH||Northern terminus of concurrency with Route 63|
|60.7||97.7||NH 10 north – Keene||Continuation into New Hampshire|
|1.000 mi = 1.609 km; 1.000 km = 0.621 mi|
- Executive Office of Transportation, Office of Transportation Planning - 2005 Road Inventory
- Daniel, Mac (July 26, 2005). "Word to road crews: Tuscaloosa is over 1,000 miles thataway". The Boston Globe. Retrieved 2009-12-31.
- "Alabama road signs in Massachusetts?". WSFA-TV. Retrieved 2009-12-31.