His career is overshadowed by that of his former student and one-time partner, Frank Furness (Fraser, Furness & Hewitt: 1867-71), whose influence is visible in Fraser's Washington, D.C. mansions for James G. Blaine and John T. Brodhead.
He served as acting supervisory architect for the U.S. Treasury (December 1878 - May 1879), created a master plan for the U.S. Capitol grounds, and served on the commission to complete Robert Mills's Washington Monument.
He was one of the founders of the Philadelphia chapter of the American Institute of Architects.
He maintained a residence in Riverton, New Jersey, and designed a number of buildings there. By 1888, he had entered into a partnership with his son Archibald, and continued working until about 1902.
- Union League of Philadelphia, 140 South Broad Street, Philadelphia, Pennsylvania (1864–65).
- Joseph Bates House, 18th & Delancey Streets, Philadelphia, Pennsylvania (1867–68), with Frank Furness and George Hewitt.
- Manufacturers' National Bank, 27 North 3rd Street, Philadelphia, Pennsylvania (1870), with Frank Furness and George Hewitt.
- British Legation, Washington DC, D.C. (1872, demolished 1931)
- General Plan for the Extension of the U.S. Capitol Grounds, Washington, D.C. (1874)
- Calvary Presbyterian Church, Riverton, New Jersey (1878–79)
- Brodhead-Bell-Morton Mansion, 1500 Rhode Island Ave. NW, Washington, D.C. (1879)
- James G. Blaine Mansion, 2000 Massachusetts Ave. NW, Washington, D.C. (1881).
- Christ Episcopal Church, Riverton, New Jersey (1884)
- Alhambra Theatre, Dunfermline, Fife, Scotland (1922) 
Brodhead-Bell-Morton Mansion, Washington, D.C. (1879).
James G. Blaine Mansion, Washington, D.C. (1881).
- George E. Thomas, Jeffrey A. Cohen & Michael J. Lewis, Frank Furness: the Complete Works (Princeton University Architectural Press, 1991 revised 1996), p. 305.
- John Fraser from Philadelphia Architects & Buildings
- "John Fraser". www.findagrave.com. Retrieved 6 April 2019.
- Bates House from Flickr.
- Manufacturers' Nation Bank from Flickr.
- U.S. Capitol Grounds from Library of Congress
- Calvary Presbyterian Church[permanent dead link]
- Brodhead-Bell-Morton Mansion from Historical Marker Database
- "Christ Church Riverton - Home". www.christriverton.org. Retrieved 27 September 2018.
- https://www.internetcreation.net. "The Alhambra Theatre Dunfermline". www.alhambradunfermline.com. Retrieved 27 September 2018.