|Maintained by INDOT|
|Length||59.563 mi (95.857 km)|
|Length||36.896 mi (59.378 km)|
|South end||US 40|
| US 136 in Jamestown|
|North end||SR 47 in Thorntown|
|Length||22.667 mi (36.479 km)|
|South end||US 421 / SR 38 / SR 39 near Frankfort|
| SR 26 near Sedalia|
SR 18 in Flora
|North end||SR 218 in Camden|
|Counties||Boone, Hendricks, Putnam, Carroll, Clinton|
The southern section is about 37 miles (60 km) long. It begins at U.S. Route 40 at the Putnam-Hendricks county line and runs northward through the towns of Coatesville and North Salem in Hendricks County, and Jamestown and Advance in Boone County. There is a junction with U.S. Route 136 at Jamestown, and a junction with Interstate 74 just to the north. The northern terminus is at State Road 47 in the town of Thorntown.
The northern section is 22.7 miles (36.5 km) long. It begins at U.S. Route 421 / State Road 38 / State Road 39 in Frankfort in Clinton County and runs northward, crossing State Road 26 east of Rossville, and passing through the town of Flora where it crosses State Road 18. The northern terminus is at State Road 218 in the town of Camden in Carroll County.
In August 2008, the Indiana Department of Transportation awarded Carroll County a grant of $1.2 million to be used to extend the road 3 miles (4.8 km) north, to connect with the planned relocation of State Road 25.
When the Owensboro Bridge between Owensboro, Kentucky and Rockport, Indiana opened in September 1940, its northern end connected to a new nine-mile (14 km) stretch of state highway through Spencer County that directed traffic to State Road 66. As the Kentucky highway which connected to the bridge was designated Kentucky State Route 75, Indiana gave its connector road the same number.
In 1954, U.S. Route 231 was extended through Kentucky and Indiana, and the southernmost stretch of 231 in Indiana was routed along State Road 75. The Indiana Department of Highways removed State Road 75 from U.S. 231 in Spencer County by the early 1980s, along with all of U.S. 231's other concurrent designations throughout the state (others included State Road 45 and State Road 43).
|Putnam||Jefferson Township||0.000||0.000||US 40 – Brazil, Indianapolis||Southern terminus of SR 75|
|0.177||0.285||SR 240 – Greencastle|
|Hendricks||Marion Township||9.478||15.253||US 36 – Rockville, Danville|
|North Salem||17.057||27.451||SR 236 – Danville|
|Jamestown||21.787||35.063||SR 234 west – Ladoga||Western end of SR 234 concurrency|
|Boone||22.233||35.781||US 136 / SR 234 – Brownsburg, Crawfordsville||Eastern end of SR 234 concurrency and terminus of SR 234|
|I-74 – Indianapolis, Danville||Exit number 52 on I-74|
|Jefferson Township||31.365||50.477||SR 32 – Crawfordsville, Lebanon|
|Thorntown||36.896||59.378||SR 47 – Crawfordsville||Northern terminus of the southern section of SR 75|
|Gap in route|
|Clinton||Frankfort||36.897||59.380||US 421 / SR 38 / SR 39 – Delphi, Indianapolis||Southern terminus of the northern section of SR 75|
|Owen Township||46.149||74.270||SR 26 – Lafayette, Kokomo|
|Carroll||Flora||55.183||88.808||SR 18 – Delphi, Marion|
|Camden||59.563||95.857||SR 218||Northern terminus of SR 75|
|1.000 mi = 1.609 km; 1.000 km = 0.621 mi|
- Indiana Department of Transportation (July 2016). Reference Post Book (PDF). Indianapolis: Indiana Department of Transportation. Retrieved February 3, 2017.