Major League Baseball
- World Series: Baltimore Orioles over Los Angeles Dodgers (4–0); Frank Robinson, MVP
- All-Star Game, July 12 at Busch Stadium: National League, 2–1 (10 innings); Brooks Robinson, MVP
- College World Series: Ohio State
- Japan Series: Yomiuri Giants over Nankai Hawks (4–2)
- Little League World Series: Westbury American, Houston, Texas
- Senior League World Series: East Rochester, New York
Awards and honors
- Baseball Hall of Fame
- Most Valuable Player
- Cy Young Award
- Rookie of the Year
- Gold Glove Award
|American League||National League|
|AVG||Frank Robinson1 BAL||.316||Matty Alou PIT||.342|
|HR||Frank Robinson1 BAL||49||Hank Aaron ATL||44|
|RBI||Frank Robinson1 BAL||122||Hank Aaron ATL||127|
|Wins||Jim Kaat MIN||25||Sandy Koufax2 LA||27|
|ERA||Gary Peters CHW||1.98||Sandy Koufax2 LA||1.73|
|SO||Sam McDowell CLE||225||Sandy Koufax2 LA||317|
|SV||Jack Aker KC||32||Phil Regan LA||21|
|SB||Bert Campaneris KC||52||Lou Brock STL||74|
Major league baseball final standings
American League final standings
National League final standings
- January 20 – The Baseball Writers' Association of America voters elect Ted Williams to the Hall of Fame. Williams receives 282 of a possible 302 votes.
- February 28 – Seeking an unprecedented three-year $1.05 million to be divided evenly, the Los Angeles Dodgers pitchers Sandy Koufax and Don Drysdale begin a joint holdout.
- March 5 – In what will prove to be one of the more influential off-the-field events in Major League history, United Steelworkers union official Marvin Miller is elected the Executive Director of the Major League Baseball Players Association (MLBPA). Under Miller's guidance, the players' union will make major gains such as salary increases, improvements in pension benefits, and the advent of free agency and salary arbitration. Miller will occupy his position from 1966 to 1982, as the players' union was transformed into one of the strongest unions in the United States.
- March 8 – The Special Veterans Committee waives Hall of Fame election rules and inducts Casey Stengel, recently retired manager of the New York Mets.
- March 17 – Sandy Koufax and Don Drysdale escalate their threat of retirement by signing movie contracts. On March 30, they will end their 32-day holdout, signing for $130,000 and $105,000 respectively.
- April 3 – USC pitcher Tom Seaver signs with the New York Mets. He had been drafted by the Braves, but they had signed him to a minor league contract while he was still in college. This voided Seaver's remaining eligibility, and voided the contract. The Mets won a special lottery over Cleveland and Philadelphia to win the right to sign him.
- April 11 – Emmett Ashford takes the field to officiate a 5–2 Washington Senators win over the Cleveland Indians at Washington, to become officially the first African-American umpire in Major League history.
- April 12 – Over 50,000 fans show up at Atlanta–Fulton County Stadium to watch the Braves first home game in Atlanta. The Braves fall to the Pittsburgh Pirates in 13 innings, 3–2.
- April 19 - The California Angels play their first regular-season game in their new ballpark, Anaheim Stadium, in front of 31,660 fans. White Sox pitcher Tommy John is the 3-2 winner, Marcelino Lopez takes the loss for the home team. The Angels' Rick Reichardt scores the first run, with a 1-out solo home run in the bottom of the 2nd inning.
- May 7 – One day after the New York Yankees' record falls to 4–16, general manager Ralph Houk fires Johnny Keane as manager and returns to manage the team himself. Dan Topping, Jr. replaces Houk as general manager. Houk had managed the Yankees to three consecutive American League pennants from 1961 to 1963 and a World Series title during the first two of those years, but his second stint will have a far less than successful beginning. Their talent and farm system both depleted, the Yankees, after finishing in sixth place in 1965, will finish dead last—their first time doing so since 1912.
- May 8
- The San Francisco Giants trade first baseman/outfielder Orlando Cepeda to the St. Louis Cardinals for pitcher Ray Sadecki. Cepeda will go on to win the National League Most Valuable Player award in 1967 on the Cardinals' World Championship team. That same day, the Giants defeat the Cardinals 10–5 in the final game at the old Busch Stadium.
- Frank Robinson of the Baltimore Orioles hits what will be the only home run hit out of Memorial Stadium. The shot comes against Luis Tiant in the first inning of the Orioles' 8–3 victory in the second game of a doubleheader against the Cleveland Indians.
- May 12 – With 46,048 spectators in attendance for the first game at the new Busch Memorial Stadium, the St. Louis Cardinals defeat the Atlanta Braves in 12 innings, 4–3, behind a single RBI by Lou Brock. Braves outfielder Felipe Alou delivers a pair of home runs.
- May 14 – The San Francisco Giants' Willie Mays hits his then National League record 512th home run – topping another Giant, Mel Ott. San Francisco beats the Los Angeles Dodgers, 6–1, at Candlestick Park.
- June 7 – The Kansas City Athletics use the second overall pick to draft Arizona State outfielder Reggie Jackson.
- June 9 – At Metropolitan Stadium, the Minnesota Twins rock the Kansas City Athletics, 9–4, with five home runs off the bats of Rich Rollins, Zoilo Versalles, Tony Oliva, Don Mincher and Harmon Killebrew in the seventh inning. These five home runs still stand as a Major League record for the most home runs batted in a single inning, and were hit off starter Catfish Hunter (two), reliever Paul Lindblad (two), and reliever John Wyatt.
- June 10 – Sonny Siebert of the Cleveland Indians no-hits the Washington Senators 2–0 at Cleveland Stadium. The no-hitter is the first by an Indian since Bob Feller's third career no-hitter, in 1951.
- July 3 – Atlanta pitcher Tony Cloninger hits two grand slams in a game against the Giants; he thus becomes the first National League player and only pitcher in Major League history to do so. His nine RBI in a game also is a record for pitchers.
- July 9 – Astroturf is finally installed in the Astrodome outfield.
- July 12 – At St. Louis, Maury Wills' 10th-inning single scores Tim McCarver, as the National League wins 2–1 over the American League in the All-Star Game, but AL Brooks Robinson's stellar game (three hits, eight fielding chances) earns him the MVP honors.
- July 21 – Against the Washington Senators in D.C., Minnesota Twins pitcher Jim Merritt strikes out twelve in a 1–0 shutout win. Seven of the twelve are consecutive, in the middle innings, to set an American League record. The final out in Merritt's string is his mound opponent Jim Hannan, who ironically had struck out Merritt just prior to the strikeout streak beginning.
- July 25 – During his Hall of Fame induction speech, Ted Williams publicly calls on baseball to induct former great players from the Negro leagues. He specifically calls for the induction of Josh Gibson and Satchel Paige. Williams' wish becomes true 5 years later when Satchel Paige is inducted into the Hall of Fame.
- July 27 – At Dodger Stadium, Sandy Koufax of the Los Angeles Dodgers faces Jim Bunning of the Philadelphia Phillies in the first matchup of perfect game pitchers. The Dodgers defeat the Phillies 2–1 in 12 innings with neither pitcher involved in the decision; both pitchers had pitched 11 innings with Koufax giving up four hits and striking out 16 and Bunning six hits and striking out 12.
- July 29 – Mickey Mantle homers against Bruce Howard of the White Sox. It is his 494th career home run and he passes Lou Gehrig for 6th place on the all-time list. The Yankees and Al Downing beat the Chicago White Sox, 2–1.
- August 15 – The Orioles left-handed slugger Boog Powell hits 3 opposite-field homers over the left-field Green Monster at Fenway Park. Powell has 13 total bases in the game, won by Baltimore, 4–2, in 11 innings.
- August 29 – The Detroit Tigers' Denny McLain wins his 16th start of the season, even though he doesn't do it that way. He throws 229 pitches, walks 9, and allows 8 hits. However, he strikes out 11 in a 6–3 win over the Baltimore Orioles.
- September 11 – Pat Jarvis became the first strikeout victim of Nolan Ryan's career.
- September 12 – Ron Perranoski of the Los Angeles Dodgers fans the first six batters he faces and earns a 3–2 win over the New York Mets. With the help of second baseman Ron Hunt, Mets rookie shortstop Bud Harrelson picks off Lou Johnson with the hidden ball trick in the sixth.
- September 18 – At Yankee Stadium, the New York Yankees fall to last place after losing to the Minnesota Twins 5–3 in 10 innings on pinch-hitter Bob Allison's three-run home run. The Yankees will stay in the cellar for the remainder of the season, finishing there for the first time since 1912.
- September 22 – The Baltimore Orioles beat the host Kansas City Athletics, 6–1, to clinch their first American League pennant since the St. Louis Browns moved to Baltimore. Both Brooks Robinson and Frank Robinson have two runs batted in. Frank Robinson will end the year as the Triple Crown winner, the first to achieve the feat since Mickey Mantle in 1956, after hitting a .316 batting average with 49 home runs and 122 RBI.
- September 25 – Against the Los Angeles Dodgers at Wrigley Field, in a battle of Jewish-American left-handers, Ken Holtzman of the Chicago Cubs has a no-hitter broken up on a Dick Schofield single leading off the ninth. Schofield later scores on a Maury Wills single; the two hits are all Holtzman allows in a 2–1 victory over the Dodgers in what will be Sandy Koufax's final regular-season loss. The Cubs score their two runs in the first as Don Kessinger, who had walked leading off the inning, scores on Glenn Beckert's triple one batter later; Beckert later scores as Jim Lefebvre drops Ernie Banks' pop-up for what would have been the third out.
- September 26 – Willie McCovey hits his 200th career home run, helping the San Francisco Giants beat the Atlanta Braves, 8–2.
- October 2 – In the second game of a doubleheader at Connie Mack Stadium, the Los Angeles Dodgers defeat the Philadelphia Phillies 6–3 as Sandy Koufax bests Jim Bunning in what will be the final regular-season game of Koufax's career. Despite giving up the three runs in the ninth inning, Koufax goes the distance and strikes out Jackie Brandt for the final out.
- October 9 – In Game Four of the World Series, Dave McNally wrapped up a brilliant pitching display, and the first World Series Championship for the Baltimore Orioles, with a four-hit, 1–0 shutout against the Los Angeles Dodgers. Series MVP Frank Robinson hits a home run off Don Drysdale for the only run of the game and gave Baltimore a sweep of the defending World Series Champion Dodgers. The shutout completes a World Series record 332⁄3 scoreless innings pitched by Orioles pitchers, beginning with Moe Drabowsky pitching 62⁄3 innings in relief of McNally in Game One, followed by shutouts by Jim Palmer and Wally Bunker—neither of whom had pitched a shutout during the regular season. The Orioles are the last of the original eight American League franchises to win their first World Series.
- November 12 – The Los Angeles Dodgers complete an 18-game tour of Japan with a 9–8–1 record. The eight losses are the most for an MLB club touring the Far East.
- November 18 – Sandy Koufax announces his retirement from baseball due to arthritis in his left elbow. Six years later he would become the youngest player elected to the Hall of Fame.
- November 23 – Chicago White Sox outfielder Tommie Agee is voted American League Rookie of the Year, gathering 16 of the 18 votes. Kansas City Athletics pitcher Jim Nash gets the other two votes. Agee had been brought up briefly the past four seasons before finding a permanent spot in 1966.
- November 25 – Cincinnati Reds infielder Tommy Helms is voted National League Rookie of the Year with 12 of 20 first place votes, with the others going to Sonny Jackson (3), Tito Fuentes (2), Randy Hundley (1), Larry Jaster (1) and Cleon Jones (1).
- November 29 – The New York Mets trade outfielder Jim Hickman and second baseman Ron Hunt to the Los Angeles Dodgers for outfielders Tommy Davis and Derrell Griffith. Hickman had been the last of the Original Mets.
- December 1 – The Los Angeles Dodgers send former National League stolen base king Maury Wills to the Pittsburgh Pirates in exchange for infielders Bob Bailey and Gene Michael. Wills upset the Dodgers when he left the team during its recent tour of Japan.
- December 31 The Atlanta Braves make a trade with the Houston Astros. The Braves send Houston Sandy Alomar SR, Arnie Umbach and Eddie Mathews in exchange for Outfielder Dave Nicholson and pitcher Bob Bruce. The trade ends Matthews' 15-year tenure with the Braves franchise. Matthews is the only player who played with the Braves in Boston, Milwaukee and Atlanta.
- January 5 – Steve Shifflett
- January 16 – Jack McDowell
- January 19 – Anthony Young
- January 21 – Chris Hammond
- January 25 – Richie Lewis
- February 1 – Darrin Chapin
- February 1 – Eduardo Zambrano
- February 3 – Paul McClellan
- February 5 – Ray Giannelli
- February 7 – Stu Cole
- February 12 – Jeff Pico
- February 13 – Jerry Browne
- February 15 – Mélido Pérez
- February 20 – Derek Lilliquist
- February 24 – René Arocha
- February 24 – Rod Brewer
- February 27 – Chris Howard
- February 27 – Pete Smith
- March 2 – Leo Gómez
- March 3 – Francisco de la Rosa
- March 4 – Andy Mota
- March 5 – Kevin L. Brown
- March 6 – Joe Hall
- March 6 – Anthony Telford
- March 7 – Mauro Gozzo
- March 10 – Mike Timlin
- March 12 – Mike Ignasiak
- March 19 – Tony Scruggs
- March 20 – Dino Ebel
- March 20 – Blas Minor
- March 21 – Roger Smithberg
- March 22 – Sean Berry
- March 23 – Mike Remlinger
- March 25 – Tom Glavine
- March 29 – Eric Gunderson
- March 30 – Terry Bross
- April 7 – Freddie Benavides
- April 8 – Alex Sanchez
- April 11 – Steve Scarsone
- April 13 – Wes Chamberlain
- April 14 ��� David Justice
- April 14 – Greg Maddux
- April 14 – Greg Myers
- April 20 – Tony Perezchica
- April 21 – Chris Donnels
- April 22 – Mickey Morandini
- April 25 – Darren Holmes
- April 25 – Erik Pappas
- April 27 – Bob Ayrault
- April 27 – Eric Hillman
- April 28 – Jim Poole
- April 29 – Ed Correa
- April 29 – John Vander Wal
- May 1 – Armando Reynoso
- May 5 – Reggie Williams
- May 12 – Rafael Bournigal
- May 13 – Chris Nichting
- May 17 – Jack Voigt
- May 19 – Jim Campbell
- May 22 – José Mesa
- May 25 – Bill Haselman
- May 25 – Dave Hollins
- May 27 – John Jaha
- May 28 – Mike Maksudian
- June 5 – Bill Spiers
- June 7 – Heathcliff Slocumb
- June 7 – Trevor Wilson
- June 13 – Scott Coolbaugh
- June 14 – Randy Tomlin
- June 15 – Dave Liddell
- June 17 – Shawn Abner
- June 18 – Sandy Alomar Jr.
- June 22 – Jorge Brito
- June 27 – Jeff Conine
- June 28 – Frank Bolick
- June 28 – Shawn Jeter
- June 29 – Peter Hoy
- June 30 – Paul Schrieber
- July 2 – Tim Spehr
- July 3 – Moisés Alou
- July 5 – Dave Eiland
- July 6 – Jeremy Hernandez
- July 6 – Darrin Winston
- July 7 – Dave Burba
- July 7 – Jeff Shaw
- July 11 – Efraín Valdez
- July 15 – Brett Merriman
- July 19 – Tim Leiper
- July 19 – David Segui
- July 28 – Derek Lee
- July 30 – Mike Anderson
- August 2 – Tim Wakefield
- August 4 – Jeff Johnson
- August 5 – Jerry Nielsen
- August 6 – Stan Belinda
- August 8 – John Hudek
- August 9 – Bob Scanlan
- August 10 – Gerald Williams
- August 12 – Dean Hartgraves
- August 14 – Dana Allison
- August 15 – Scott Brosius
- August 15 – Dan Walters
- August 16 – Steve Foster
- August 16 – Terry Shumpert
- August 17 – Tony Barron
- August 18 – Bob Zupcic
- August 19 – Woody Williams
- August 21 – John Wetteland
- August 22 – Scott Chiamparino
- August 24 – Dean Wilkins
- August 25 – Albert Belle
- August 26 – Víctor Rosario
- August 31 – Jeff Frye
- September 2 – Terry Jorgensen
- September 8 – Mike Dyer
- September 10 – Riccardo Ingram
- September 14 – Mike Draper
- September 15 – Doug Simons
- September 23 – Pete Harnisch
- September 24 – Chris George
- September 24 – Bernard Gilkey
- September 24 – Kevin Koslofski
- September 28 – César Hernández
- October 3 – Darrin Fletcher
- October 3 – Scott Taylor
- October 4 – Tim Mauser
- October 4 – Mike Walker
- October 6 – Archi Cianfrocco
- October 8 – Jay Gainer
- October 10 – Francisco Cabrera
- October 11 – Gregg Olson
- October 12 – Jorge Pedre
- October 18 – Carlos Maldonado
- October 18 – Alan Mills
- October 19 – Dave Veres
- October 20 – Jonathan Hurst
- October 21 – Kevin Batiste
- October 25 – Mike Harkey
- October 28 – Tim Bogar
- October 28 – Juan Guzmán
- October 29 – Pat Combs
- October 30 – Mark Ettles
- October 31 – Brian Keyser
- November 1 – Bob Wells
- November 2 – Orlando Merced
- November 4 – Brian Drahman
- November 7 – William Suero
- November 7 – Andy Tomberlin
- November 11 – Dave Telgheder
- November 14 – Curt Schilling
- November 16 – Tim Scott
- November 17 – Andy Fletcher
- November 17 – Jeff Nelson
- November 18 – Ron Coomer
- November 18 – Howard Farmer
- November 18 – Eddie Tucker
- November 19 – Jeff Hartsock
- November 25 – Mark Whiten
- December 1 – Greg McMichael
- December 1 – Larry Walker
- December 4 – Darrell Sherman
- December 5 – Tony Beasley
- December 6 – Terry McDaniel
- December 10 – Norberto Martin
- December 10 – Mel Rojas
- December 18 – Eric Cooper
- December 19 – Joe Slusarski
- December 20 – Jeff Mutis
- December 21 – Paul Swingle
- December 24 – Mo Sanford
- December 29 – Luis de los Santos
- December 30 – Kevin Long
- January 1 – Oscar Dugey, 78, light-hitting infielder who appeared in 193 games for the Boston Braves and Philadelphia Phillies between 1913 and 1920; member of 1914 world-champion "Miracle Braves" and 1915 Phillies, who captured their first National League pennant.
- January 10 – Andy Reese, 61, played every position but pitcher and catcher—although primarily a left fielder and third baseman—over the course of his 331-game career with the New York Giants of 1927–1930.
- January 14 – Sidney Weil, 74, principal owner of the Cincinnati Reds from 1929 to 1933.
- January 15 – Stover McIlwain, 26, pitcher who appeared in two games as a teenager for the Chicago White Sox in 1957 and 1958.
- January 15 – Walt Walsh, 68, pinch runner for two games with the 1920 Philadelphia Phillies.
- January 20 – Leslie O'Connor, 76, lawyer and baseball executive; assistant to Commissioners K. M. Landis (1921–1944) and Happy Chandler (1945); in between, acting Commissioner of Baseball as chairman of the MLB Advisory Council (1944–1945); subsequently general manager of Chicago White Sox (1945–1948) and president of Pacific Coast League (1956–1959).
- January 29 – Homer Summa, 67, right fielder who collected a .302 average over ten seasons with the Pittsburgh Pirates (1920), Cleveland Indians (1922–1928) and Philadelphia Athletics (1929–1930); member of two-time world champion Athletics.
- January 31 – Pat Donahue, 81, catcher who got into 119 games between 1908 and 1910 for the Boston Red Sox, Philadelphia Athletics and Cleveland Naps.
- February 4 – Mike Milosevich, 51, shortstop in 124 games for the 1944–1945 New York Yankees.
- February 14 – Jack Coffey, 79, infielder who played from 1909 to 1918 for the Boston Doves, Detroit Tigers and Boston Red Sox who was also a longtime baseball head coach at Fordham University.
- February 17 – Finners Quinlan, 78, outfielder who played 13 games for the 1913 St. Louis Cardinals and 42 more for the 1915 Chicago White Sox.
- February 18 – Marty McManus, 65, second baseman and third baseman who played 1,831 games from 1920 through 1934 for the St. Louis Browns, Detroit Tigers, Boston Red Sox and Boston Braves; player-manager of the Red Sox in 1932 and 1933.
- February 20 – Harry Geisel, 77, American League umpire from 1925 to 1942.
- February 25 – Garland Braxton, 65, left-handed pitcher in 282 games for the Boston Braves, New York Yankees, Washington Senators, Chicago White Sox and St. Louis Browns between 1921 and 1933; led American League in earned run average (2.51) in 1928.
- March 9 – Aaron Robinson, 50, All-Star catcher (1947) for the New York Yankees who succeeded Bill Dickey, then was replaced by Yogi Berra as the Bombers' starting receiver in 1948; played for the Chicago White Sox, Detroit Tigers and Boston Red Sox from 1948 through 1951.
- March 9 – Elmer Steele, 81, pitcher in 75 games for Boston of the American League and Pittsburgh and Brooklyn of the National League between 1907 and 1911.
- March 14 – Lee Magee, 76, outfielder-second baseman for seven big-league teams, principally the St. Louis Cardinals and New York Yankees, in the nine seasons of 1911–1919, appearing in 1,015 games; player-manager of Brooklyn Tip-Tops of the "outlaw" Federal League for most of 1915; known for bitter battles with owners, and accused them of "blackballing" him after 1919 season; implicated, with Hal Chase, in gambling allegations investigated by Cook County grand jury called in 1920 to probe the "Black Sox" scandal.
- March 15 – Chappie Geygan, 62, shortstop and third baseman who played in 40 games for the Boston Red Sox between 1924 and 1926.
- March 18 – Frank Bennett, 61, pitcher in five games for the Boston Red Sox (1927–1928).
- March 20 – "Jughandle Johnny" Morrison, 70, pitcher who won 103 career games for the Pittsburgh Pirates (1920–1927) and Brooklyn Robins (1929–1930); member of 1925 world champions.
- March 25 – Bill Morrisette, 71, pitcher who worked in 13 total games for the 1915–1916 Philadelphia Athletics and 1920 Detroit Tigers.
- March 31 – Grady Adkins, 68, pitcher in 67 games for the 1928–1929 Chicago White Sox.
- April 1 ��� John Sullivan, 76, outfielder who got into 162 total games for the Boston Braves (1920–1921) and Chicago Cubs (1921).
- April 5 – Sam Dodge, 76, pitcher in four games for the 1921–1922 Boston Red Sox.
- April 6 – Rolla Mapel, 76, left-handed pitcher in four games for 1919 St. Louis Browns.
- April 12 – Joe Harris, 84, pitcher with the Boston Americans from 1905–1907; posted a 2–21 won–lost record in 1906, and followed that in 1907 by going 0–7; his career mark was 3–30 (.091 winning percentage) with a 3.35 earned run average.
- April 19 – Maury Kent, 80, pitcher in 23 games during 1912–1913 for Brooklyn of the National League; coached multiple sports (especially baseball) in U.S. colleges (notably Northwestern University) until 1943.
- April 22 – Lou Finney, 55, outfielder-first baseman who played in 1,270 games between 1931 and 1947 for the Philadelphia Athletics, Boston Red Sox, St. Louis Browns and Philadelphia Phillies.
- April 25 – Art Decatur, 72, pitcher who appeared in 153 games between 1922 and 1927 for the Brooklyn Robins and Philadelphia Phillies.
- May 4 – Bob Elliott, 49, seven-time National League All-Star third baseman and 1947 NL Most Valuable Player whose 15-year MLB career (1939–1953) was primarily spent with the Pittsburgh Pirates and Boston Braves; manager of 1960 Kansas City Athletics.
- May 7 – Bing Miller, 71, outfielder who batted .311 in 1,820 games between 1921 and 1936 for the Washington Senators, Philadelphia Athletics, St. Louis Browns and Boston Red Sox, who won two World Series with the Athletics in 1929 and 1930; later a longtime coach.
- May 26 – Bill Rumler, 75, catcher, outfielder and frequent pinch hitter who appeared in 139 games for the St. Louis Browns in 1914 and 1916–1917.
- May 29 – Hippo Vaughn, 78, left-handed pitcher who won 178 games for the New York Highlanders (1908; 1910–1912), Washington Senators (1912) and Chicago Cubs (1913–1921), including five 20-win-or-more seasons for the Cubs; known for the May 2, 1917, game in which he and Cincinnati pitcher Fred Toney each threw nine innings of no-hit ball; the "double no-hitter" ended in the tenth when Vaughn surrendered two hits and an unearned run, with Toney notching a 1–0 no-hit victory.
- June 8 – Jake Munch, 75, outfielder-first baseman in eight games for the 1918 Philadelphia Athletics.
- June 14 – Bill Walker, 62, left-handed pitcher for the New York Giants (1927–1932) and St. Louis Cardinals (1933–1936); member of 1934 world champion "Gashouse Gang"; two-time National League earned-run average champion, 1929 (3.09) and 1931 (2.26).
- June 18 – Rollie Naylor, 74, pitcher for a succession of execrable Philadelphia Athletics teams, in 1917 and from 1919 through June 1924; lost 23 games in 1920.
- June 25 – Mose Solomon, 65, first baseman in two games for the 1923 New York Giants; minor-league slugger nicknamed "The Rabbi of Swat" and "The Jewish Babe Ruth."
- June 26 – Lil Stoner, 67, pitcher in 229 games in the majors, 217 of them with the Detroit Tigers, between 1922 and 1931.
- June 27 – Marty Krug, 77, third baseman who played for the Boston Red Sox (1912) and Chicago Cubs (1922); later, an MLB scout and minor-league manager.
- July 5 – Pete Fox, 57, outfielder for the Detroit Tigers and Boston Red Sox who batted .298 lifetime in 1,461 games between 1933 and 1945; hit .327 for Tigers with 18 hits in 14 World Series games (1934, 1935, 1940), winning a ring in 1935.
- July 6 – Sad Sam Jones, 73, pitcher who enjoyed a 22-year year career (1914–1935) in the majors, posting a 229–217 record in 647 games for the Cleveland Indians, Boston Red Sox, New York Yankees, Washington Senators, St. Louis Browns and Chicago White Sox; member of 1918 world champion Boston and 1923 world champion New York clubs.
- July 9 – Mule Suttles, 66, All-Star first baseman of the Negro leagues who hit the first home run in the East-West All-Star game.
- July 11 – Barney Lutz, 50, former minor league outfielder and manager, died while scouting a New York–Penn League game for the Baltimore Orioles.
- July 13 – Rip Vowinkel, 81, pitcher who worked in five games for the 1905 Cincinnati Reds.
- July 15 – Tommy McMillan, 78, shortstop for the Brooklyn Superbas, Cincinnati Reds and New York Highlanders between 1908 and 1912; played 22 years in minor leagues.
- July 16 – Elmer Yoter, 66, third baseman for the Philadelphia Athletics, Cleveland Indians and Chicago Cubs in 36 games over four seasons between 1921 and 1928; longtime minor league manager and MLB scout.
- July 22 – Frank Delahanty, 83, light-hitting outfielder for New York (1905–1906) and Cleveland (1907) of the American League and Buffalo (1914) and Pittsburgh (1914–1915) of the "outlaw" Federal League; one of five Delahanty brothers to appear in the major leagues.
- July 28 – Hal Dixon, 46, National League umpire from 1953 through 1959.
- August 1 – Hank Gowdy, 76, catcher who appeared in 1,050 games in the National League, 852 with Boston and remaining 198 with New York; member of 1914 "Miracle Braves", when he helped win the World Series by batting .545 with six hits (five for extra bases) in four games; later a longtime coach; the only MLB player to have served in both World Wars.
- August 4 – Pug Cavet, 76, pitcher whose 23-year professional career included 49 games for the Detroit Tigers (1911 and 1914–1915).
- August 10 – Chuck Dressen, 71, incumbent manager of the Detroit Tigers since June 18, 1963, and pilot of four other MLB clubs dating to 1934; led the Brooklyn Dodgers to pennants in 1952–1953; in his playing days, a third baseman who appeared in 646 games for the Cincinnati Reds and New York Giants between 1925 and 1933.
- August 11 – Ellis Ryan, 62, principal owner of the Cleveland Indians from 1949 to 1952.
- August 15 – George J. Burns, 76, outfielder who played in 1,844 games between 1911 and 1925, primarily with the New York Giants; led the National League in runs and walks five times each.
- August 17 – Bill Allington, 62, manager who won four Championship Titles in the All-American Girls Professional Baseball League.
- August 24 – Wheezer Dell, 80, pitcher who appeared in 92 career games for the 1912 St. Louis Cardinals and 1915–1917 Brooklyn Robins.
- August 25 – Ray Rolling, 79, second baseman in five games for 1912 St. Louis Cardinals.
- August 25 – Sam Zoldak, 47, left-handed pitcher who appeared in 250 games for the St. Louis Browns, Cleveland Indians and Philadelphia Athletics between 1944 and 1952.
- August 29 – Al DeVormer, 75, catcher for the Chicago White Sox, New York Yankees, Boston Red Sox and New York Giants between 1918 and 1927.
- August 29 – Bobby Schang, 79, catcher whose 17-year pro career (1912–1928) was punctuated by getting into 82 major-league games with the Pittsburgh Pirates (1914–1915), New York Giants (1915) and St. Louis Cardinals (1927); brother of Wally Schang.
- September 9 – Bob Kelley, 48, Los Angeles sportscaster and voice of the expansion Angels during their maiden 1961 season in the American League; longtime voice of NFL's Los Angeles Rams.
- September 12 – Parson Perryman, 77, pitcher in 24 games for the 1915 St. Louis Browns.
- September 12 – Bill Summers, 70, American League umpire from 1933 to 1959 who worked in eight World Series and a record seven All-Star games.
- September 13 – Ralph Comstock, 78, pitched in the 1910s for the Detroit Tigers, Boston Red Sox, Pittsburgh Rebels (of the "outlaw" Federal League) and Pittsburgh Pirates.
- October 2 – Jumbo Brown, 59, a 295 lb (134 kg) pitcher who worked in 249 games, 226 in relief, for five MLB teams between 1925 and 1941; led National League in saves (not then an official statistic) in 1940 and 1941.
- October 4 – Mike Tresh, 52, catcher for the Chicago White Sox and Cleveland Indians from 1938 to 1949 and the father of New York Yankees' Tom Tresh.
- October 7 – George Magerkurth, 77, National League umpire from 1929 to 1947.
- October 10 – Patsy Gharrity, 74, catcher who appeared in 676 big-leagues games for the Washington Senators (1916–1923; 1929–1930); longtime batterymate of Hall of Fame pitcher Walter Johnson.
- October 11 – Red Smith, 76, solid third baseman for Brooklyn and Boston of the National League from 1911 through 1919; in his only year with Boston, he was a member of the 1914 World Series champion "Miracle Braves".
- October 17 – Bob Swift, 51, MLB catcher (1940–1953), coach, and acting manager of the 1965 and 1966 Detroit Tigers, who was behind the plate when the diminutive Eddie Gaedel made his famous appearance as a pinch hitter on August 19, 1951.
- October 23 – Fred Fussell, 71, left-handed pitcher who worked in 80 games for the Chicago Cubs (1922–1923) and Pittsburgh Pirates (1928–1929).
- October 26 – Bill "Crungy" Cronin, 63, catcher in 126 games for 1928–1931 Boston Braves, who played professionally for 23 seasons.
- October 29 – Al Grabowski, 65, pitcher who appeared in 39 total games for 1929–1930 St. Louis Cardinals.
- October 30 – "Kewpie Dick" Barrett, 60, pitcher who appeared in 141 MLB games between 1933 and 1945 for four teams; legendary minor-league hurler, where he won 317 career games; seven-time 20-game winner for Seattle of the Pacific Coast League; The Sporting News' Minor League Player of the Year in 1942.
- October 30 – Rex Cecil, 50, pitcher in 18 games for the 1944–1945 Boston Red Sox, including the Bosox' starting assignment on Opening Day 1945.
- October 30 – Alex Pearson, 89, pitcher in 15 career games for the St. Louis Cardinals (1902) and Cleveland Naps (1903).
- November 1 – Earl Blackburn, 73, backup catcher for four National League clubs who appeared in 71 games between 1912 and 1917.
- November 2 – Lew Moren, 83, pitcher who worked in 141 games for the Pittsburgh Pirates (two total appearances in 1903–1904) and Philadelphia Phillies (139 games between 1907 and 1910).
- November 7 – Rube Bressler, 72, one of only a few players in major league baseball history to successfully convert from a pitcher to a position player as a first baseman/outfielder, who played for the Philadelphia Athletics and Phillies, Brooklyn Dodgers, Cincinnati Reds, and St. Louis Cardinals between 1914 and 1931.
- November 21 – Hack Miller, 53, catcher who appeared in only seven total games for the 1944–1945 Detroit Tigers, but homered in his first major-league at bat.
- November 24 – Tom Gulley, 66, outfielder who played briefly with 1923–1924 Cleveland Indians and 1926 Chicago White Sox.
- December 11 – Cliff Fannin, 42, pitcher in 164 games for the St. Louis Browns between 1945 and 1952.
- December 20 – Doc Farrell, 64, utility infielder for six different teams between 1925 and 1935, including the Yankees 1932 World Champions.
- Baseball Almanac - Major League Baseball Players Who Died in 1966
- Baseball Reference - 1966 MLB Season Summary
- ESPN - 1966 MLB Season History