During the English Civil War Sands was a colonel with a regiment in the Royalist army. As acting Governor of Worcester he successfully held the city for the Royalists during the Siege of Worcester (1643) against a Parliamentary army commanded by Sir William Waller.
In about 1654 the family mansion of The Vine, erected by William Sandys, 1st Baron Sandys, in the reign of Henry VIII was either sold, or it passed by forfeiture or composition, to Chaloner Chute, Member of Parliament for Middlesex in the Second Protectorate Parliament of 1656 and briefly its Speaker.
After the Restoration Sands was summoned to parliament on 8 May 1661. He died in 1668, and was succeeded by his brother Henry Sandys, 7th Baron Sandys, who was summoned to parliament on 6 March 1679.
- Banks, Thomas Christopher (1808), The Dormant and Extinct Baronage of England: Or, An Historical and Genealogical Account of the Lives, Public Employments, and Most Memorable Actions of the English Nobility who Have Flourished from the Norman Conquest, J. White, p. 456
- Burke, John (1846), A General and Heraldic Dictionary of the Peerages of England, Ireland, and Scotland, extinct, dormant, and in abeyance ... England, Henry Colburn, p. 464
- Willis-Bund, John William (1905), The Civil War In Worcestershire, 1642-1646: And the Scotch Invasion Of 1651, Birmingham: The Midland Educational Company