|Maintained by VDOT|
|Length||29.81 mi (47.97 km)|
| Journey Through Hallowed Ground Byway|
|West end||US 250 in Shadwell|
| SR 231 in Cismont|
SR 208 in Louisa
|East end||US 522 / SR 208 in Mineral|
State Route 22 (SR 22) is a primary state highway in the U.S. state of Virginia. The state highway runs 29.81 miles (47.97 km) from U.S. Route 250 in Shadwell east to US 522 and SR 208 in Mineral. SR 22 is one of two primary east–west highways in Louisa County, connecting the county seat of Louisa with Charlottesville and Mineral. The state highway runs concurrently with US 33 through Louisa and with SR 208 between Louisa and Mineral.
SR 22 begins at a tangent intersection with US 250 (Richmond Road) in the community of Shadwell in eastern Albemarle County. The state highway heads northeast as Louisa Road, a two-lane road that parallels CSX's Piedmont Subdivision and passes under Interstate 64. The state highway and railroad diverge in the hamlet of Keswick. SR 22 meets the southern end of SR 231 (Gordonsville Road) in Cismont and crosses over the Piedmont Subdivision rail line in Cobham before entering Louisa County. The state highway intersects US 15 in the hamlet of Boswells Tavern, also known as Waldrop, and crosses the upper reaches of the South Anna River.
SR 22 begins to run concurrently with US 33 (Spotswood Trail) at Trevilians, where the state highway begins to parallel the railroad again. The two highways enter the town of Louisa as Main Street. At the east end of the downtown area, SR 22 and US 33 intersect SR 208 (Courthouse Road), which joins the two other highways east a short distance to where US 33 diverges as Jefferson Highway. SR 22 and SR 208 continue east parallel to the railroad along Davis Highway, which passes to the north of Louisa County Airport. East of Louisa County High School, the two highways turn south into the town of Mineral, where the two highways follow Piedmont Avenue. SR 22 reaches its eastern terminus at the highways' intersection with US 522. US 522 heads south as Mineral Avenue through downtown Mineral. The northbound direction of the U.S. Highway and SR 208 turn east onto 1st Street, cross the railroad tracks at grade, then turn north on Louisa Avenue to exit the town.
|Albemarle||Shadwell||0.00||0.00||US 250 (Richmond Road) – Zion Cross-Roads, Charlottesville, Staunton||Western terminus|
|Cismont||5.35||8.61||SR 231 north (Gordonsville Road) – Gordonsville, Madison||Southern terminus of SR 231|
|Louisa||Boswells Tavern||13.05||21.00||US 15 (James Madison Highway) – Gordonsville, Farmville|
|Trevilians||19.28||31.03||US 33 west (South Spotswood Trail) – Gordonsville, Harrisonburg||West end of concurrency with US 33|
|Louisa||SR 669 (Ellisville Drive)||former SR 27 north|
|24.20||38.95||SR 208 west (Courthouse Road) to I-64 – Ferncliff||West end of concurrency with SR 208; former SR 27 south|
|24.60||39.59||US 33 east (Jefferson Highway) – Richmond||East end of concurrency with US 33|
|Mineral||29.81||47.97||US 522 / SR 208 east / SR 1112 (Mineral Avenue / First Street) to SR 618 – Cuckoo, Spotsylvania, Culpeper, Bumpass||Eastern terminus; east end of concurrency with SR 208|
|1.000 mi = 1.609 km; 1.000 km = 0.621 mi|
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