Thug life may refer to:
- Thug Life, an American hip hop group including Tupac Shakur
- Thug Life: Volume 1, the only album released by Thug Life
- Tupac: A Thug Life, a book about Tupac Shakur
- "The Hate U Give Little Infants Fucks Everybody", an acronym devised by Tupac Shakur
- The Hate U Give, a young adult novel by Angie Thomas
- The Hate U Give (film), a 2018 film based on the novel
- "Thug Life", a song from the album Iridescence by American boyband Brockhampton
- "Thug Life", a song from the album Issa Album by American rapper 21 Savage
- "Thug Life", a song from the album Pray 4 Love by American rapper Rod Wave
- Thug Law: Thug Life Outlawz Chapter 1, a compilation album by American rapper Big Syke
- Thug Life (film), a 2001 film directed by Greg Carter
- Thug life (concept), in gangsta rap music
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