|Maintained by SCDOT|
|Length||29.0 mi (46.7 km)|
|West end||US 21 / US 76 / US 176 / US 321 in Columbia|
|East end||US 601 in Wateree|
SC 48 begins in downtown Columbia along Assembly Street. It traverses west, passing alongside the South Carolina State House and the University of South Carolina, before turning onto Rosewood Drive and then onto Bluff Road. After leaving the Columbia city limits, it continues through southeastern Richland County as a two-lane rural highway to U.S. Route 601 (US 601).
Established in 1930 as a new primary routing, it originally traversed from Gervais Street, going east along Assembly Street, to US 601 in Wateree. Various adjustments in its downtown routing have been made between 1937-46. In 1950, SC 48 was straightened out between Gadsden and Wateree, leaving behind Old Bluff Road. In 1978, SC 48 was extended west to its current western terminus at Elmwood Avenue.
The entire route is in Richland County.
|Columbia||0.0||0.0||US 21 / US 76 / US 176 / US 321 (Elmwood Avenue) – Spartanburg, Greenville, Chester, Rock Hill|
|0.5||0.80||SC 12 (Taylor Street) – Lexington||To Fort Jackson|
|1.0||1.6||US 1 / US 378 (Gervais Street)|
|1.5||2.4|| To US 21 south to US 176 west to US 321 south (West Blossom Street) – Cayce|
To US 76 east to US 378 east (East Blossom Street) – Sumter
|To Columbia Metropolitan Airport|
To Fort Jackson
|2.5||4.0||SC 16 (Rosewood Drive)|
|5.4||8.7||SC 768 east (Beltline Boulevard)|
|5.6||9.0||I-77 – Charleston, Charlotte||I-77 exit 5.|
|||17.7||28.5||Mountain View Road||To Congaree National Park|
|Gadsden||21.2||34.1||SC 769 (Congaree Road) – Congaree|
|Wateree||29.0||46.7||US 601 (McCords Ferry Road) – St. Matthews, Orangeburg, Camden|
|1.000 mi = 1.609 km; 1.000 km = 0.621 mi|