|Representing Great Britain|
|2012 London||Individual compound|
|2008 Beijing||Individual compound|
In 2003, she became the first disabled archer from Europe to take part in an able-bodied event at international level, however it was during this event that she contracted Lyme disease. She lost sight in her aiming eye and had to remodel her shooting style to compensate, developing a stance with her head tilted back to make best use of her working eye.
At the 2008 Summer Paralympics, held in Beijing, China, she won a bronze medal in the women's individual compound event. Having been defeated by fellow British competitor Danielle Brown in the semifinal with a score of 113-105, Clarke beat Turkey's Gulbin Su in the bronze playoff to win the medal.
In 2009, she won a gold medal in the team event and a silver in the individual at the World Championships held in the Czech Republic. She was overwhelmed 114-107 by teammate and reigning Paralympic Champion Danielle Brown in the final of the individual event.
In the 2010 European Championships Clarke did not rank highly in the individual event, but won a silver medal with the women's compound team. Teammates Danielle Brown and Pippa Britton won the individual gold and silver respectively. Clarke also failed to make the team for the 2011 World Championships, beaten to the mark by Danielle Brown, Pippa Britton and Sarah Beamish.
Clarke was selected to compete for Great Britain at the 2012 Summer Paralympics in London, United Kingdom. She took part in the women's individual compound event and advanced to the final to face compatriot Brown. The first two sets were tied before Brown won the third and Clarke the fourth to force a fifth set. Clarke was left needing to score a ten with her final arrow to take the match to a shoot-off, however she was unable to capitalise on this and scored a seven meaning she won the silver medal.
- "Mel Clarke". British Paralympic Association. Retrieved 5 September 2012.
- Rudd, Melissa (19 August 2008). "Clarke takes aim at Beijing medal". BBC Sport. Retrieved 5 September 2012.
- Barkham, Patrick (4 September 2012). "Paralympics 2012: Danielle Brown retains title in Great Britain one-two". The Guardian. Retrieved 5 September 2012.
- Scott-Elliot, Robin (5 September 2012). "Archery: Brown holds her nerve to win battle of Britain". The Independent. Retrieved 5 September 2012.
- "Archery gold for Brown and Stubbs". BBC Sport. 13 September 2008. Retrieved 5 September 2012.
- "Brown retains world archery title". BBC Sport. 22 August 2009. Retrieved 5 September 2012.
- "Paralympics 2012: Mel Clarke overjoyed after winning archery silver". Retrieved 2012-09-05.