This article relies largely or entirely on a single source. (February 2017)
He was a cardinal elector at the papal conclave of 1549-50 that elected Pope Julius III. The new pope made Crescenzi papal legate in Bologna. He was the Camerlengo of the Sacred College of Cardinals from January 19, 1551 to January 8, 1552. The pope named him to a commission on church reform on February 18, 1551, and on March 4, 1551 named him legate a latere to the Council of Trent.