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One of the three talukas (sub-districts) of Shikarpur, Garhi Yasin is of political and historical significance to Pakistan. On 1 June 1977 the old Shikarpur subdivision, consisting of the two talukas of Shikarpur and Garhiyasin, was separated from Sukkur District, and a new District Shikarpur was created and attached to Larkana Division.
Garhi Yasin is an extremely wealthy town located in the north of Sindh province of Pakistan. It is the second largest town of the district Shikarpur, having population of more than 14,000. Garhi Yasin is situated on the right bank of River Indus. Garhi Yasin region has always been important because of proximity of Shikarpur, a place that commanded the trade route through the Bolan Pass, and its merchants had dealings with many towns in Central Asia.
Garhi Yasin taluka comprises two main towns Dakhan, Madeji and some main villages Haji Rohelo Khan Jaffri, and Bado. Garhi Yasin has produced Politicians, Civil Servants, like Agha Siraj Khan Durrani, Speaker of Sindh assembly and Agha Rafique Khan Durrani former chief justice of sharia law and Chairman of the SPSC. The town is named after its founder Yasin Khan Pathan. Sindhi is the common language of the people in this region. The Jamali, Jaffri, Mangi, Marfani Kalhora, Mughal, Pirzada, Seelro, Wadhio, Chandio, Memon, Sindhi Hindu, Soomra, Shaikh, khakhrani, Syed, Mirani, Qazi, Bhutta, Lashari, Rahooja, Bhatti, Mahar, Jakhro, Kakepota, Arain, Mangi, Malik, Ghori, Rajpoot, Bhayo Tribe, Dharejo and Aawaan. With the Pathan(Durrani,Babar & Barak zai) From which the Durrani tribe being the strongest both politically and by land. After the independence from British India, Many Hindu and Sikh clans migrated to India. There also Hindus settled in Garhi Yasin. One of the Chiefs of Ghari Yasin; is Agha Affan Durrani holding tremendous political power and known to be influential all over the country.
The town has a Higher Secondary School Agha Badaruddin Khan Durrani and three high schools, several primary schools, a Mono Technique School and a vocational School for typing, commercial, computer etc.
A considerable part of the area is irrigated. Major productions of the area are rice, wheat and pulses beside Maize, sugarcane, vegetables fruits etc.
It has a small market and manufactures of handicrafts, metal ware, furniture, bricks and pottery. Hand-loom weaving of the area used to be very popular. Rilly of Garhi Yasin is very popular in all over Sindh and making a good variety of Sindhi topi and Balochi Rilly in different models.
It is chiefly alluvial plain. The lands are greatly suffered after construction of barrage at Sukkur and being rapidly converted into salt lands (Kalar). Waterlogging and salinity is a major problem of Garhi Yasin. The climate is very hot as it reached 49°C last year 2016, dry and enervating. Winter in mild and is best time to visit this town.