His brothers Charles Germain de Saint Aubin and Augustin de Saint-Aubin were also artists, as was his niece, Marie-François, daughter of Charles. He was a student of Étienne Jeaurat and Hyacinthe Collin de Vermont. After three failures to win a Prix de Rome from 1752 to 1754, he left the Académie des Beaux-Arts and joined the Guild of Saint Luke.
A distinctive aspect of Saint-Aubin's art is its inordinate fondness for observation of society on the streets of the capital, which he sketched scenes or entertainment in his wanderings. As such, his engravings etchings and large watercolors are a valuable record of the Parisian artistic life in the eighteenth century.
- Profile of Marie-Françoise de Saint-Aubin in the Dictionary of Pastellists Before 1800.
- E. and J. de Goncourt, The Art of the eighteenth century, the Saint-Aubin
- Catalogue of rare and valuable books composing the library of Mr. Hippolyte Destailleur ... Paris: D. Morgand, 1891. 8 °, 448 p.
- Liedtke , Walter A. (1984). Flemish paintings in the Metropolitan Museum of Art. New York: The Metropolitan Museum of Art. ISBN 0870993569. (see index, v.1).
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