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|Champions||Nepal Police Club|
|Relegated||Boys Union Club|
|2011 AFC President's Cup||Nepal Police Club|
|Goals scored||357 (2.29 per match)|
|Top goalscorer||Santosh Sahukhala (19)|
The 2010 Martyr's Memorial A-Division League (known as the Martyrs' Memorial San Miguel 'A' Division League Football Tournament 2010 for sponsorship reasons) was the 38th season of the A-Division League since its establishment in 1954/55. A total of 12 teams competed in the league. The season began on 12 February 2010 and concluded on 14 June 2010.
Defending champion Nepal Police Club has won the league with two matches remaining.
1971 League Champion Boys Union Club relegated to B Division after 58 years in league history by the goal difference with APF Club having the equal 22 points whereas losing the 15 matches among 22 three times league champion Sankata Club also relegated to B Division after 37 years.
|Pos||Team||Pld||W||D||L||GF||GA||GD||Pts||Qualification or relegation|
|1||Nepal Police Club (C)||22||14||8||0||35||8||+27||50||Qualification for 2011 AFC President's Cup|
|2||Three Star Club||22||12||7||3||41||15||+26||43|
|3||New Road Team||22||12||4||6||39||29||+10||40|
|4||Nepal Army Club||22||11||6||5||38||21||+17||39|
|5||Manang Marshyangdi Club||22||8||6||8||30||32||−2||30|
|6||Machhindra Football Club||22||7||6||9||20||27||−7||27|
|7||Jawalakhel Youth Club||22||7||6||9||27||43||−16||27|
|9||Ranipokhari Corner Team||22||6||5||11||24||31||−7||23|
|11||Boys Union Club (R)||22||6||4||12||28||39||−11||22||Relegation to 2013 Martyr's Memorial B-Division League|
|12||Sankata Club (R)||22||5||2||15||20||35||−15||17|
Rules for classification: 1) points; 2) goal difference; 3) number of goals scored.
(C) Champion; (R) Relegated.
|Best Coach||Birat Krishna Shrestha||Nepal Police Club|
|Best Goalkeeper||Kiran Chemjong||Three Star Club|
|Best Defender||Rohit Chand||Machhindra Football Club|
|Best Midfielder||Parbat Pandey||Nepal Police Club|
|Best Striker||Santosh Sahukhala||Nepal Police Club|