|1959 Chicago Cardinals season|
|Head coach||Pop Ivy|
|Owner||Violet Bidwill Wolfner|
|Home field||Soldier Field &|
|Division place||6th NFL Eastern|
|Playoff finish||did not qualify|
The 1959 Chicago Cardinals season was the team's 40th and final season in Chicago. The Cardinals opened the season with a 49–21 home win over the Washington Redskins at Soldier Field, but finished with a record of two wins and ten losses, last place in the Eastern Conference. They tied with the Los Angeles Rams for the worst record in the 12-team league.
Their final home game in Chicago was on November 29, a 31–7 loss to the cross-town rival Bears at Soldier Field. The home games of October 25 and November 22, both losses, were played in Minnesota at Metropolitan Stadium in Bloomington, the future home of the expansion Minnesota Vikings, starting two years later in 1961.
|1||September 27||Washington Redskins||W 49–21||1–0||Soldier Field|
|2||October 4||Cleveland Browns||L 34–7||1–1||Soldier Field|
|3||October 11||at Washington Redskins||L 23–14||1–2||Griffith Stadium|
|4||October 18||at Cleveland Browns||L 17–7||1–3||Cleveland Stadium|
|5||October 25||Philadelphia Eagles||L 28–24||1–4||Metropolitan Stadium|
|6||November 1||Pittsburgh Steelers||W 45–24||2–4||Soldier Field|
|7||November 8||at New York Giants||L 9–3||2–5||Yankee Stadium|
|8||November 15||at Philadelphia Eagles||L 27–17||2–6||Franklin Field|
|9||November 22||New York Giants||L 30–20||2–7||Metropolitan Stadium|
|10||November 29||Chicago Bears||L 31–7||2–8||Soldier Field|
|11||December 6||at Detroit Lions||L 45–21||2–9||Briggs Stadium|
|12||December 13||at Pittsburgh Steelers||L 35–20||2–10||Forbes Field|
|NFL Eastern Conference|
|New York Giants||10||2||0||.833||8–2||284||170||W4|
Note: Tie games were not officially counted in the standings until 1972.
- "NFL standings: final". Milwaukee Sentinel. December 14, 1959. p. 4, part 2.
- "Bears stay alive with 31-7 win". Milwaukee Sentinel. UPI. November 20, 1959. p. 2, part 2.
- "Cardinals blow lead, lose to Philadelphia". Milwaukee Journal. Associated Press. October 26, 1959. p. 14, part 2.
- "Giants beat Cards, take Eastern lead". Milwaukee Journal. Associated Press. November 23, 1959. p. 18, part 2.
- "National Football League's Cards to move to St. Louis". Ocala Star-Banner. Florida. Associated Press. March 14, 1960. p. 8.
- "Chicago Cardinals to move to St. Louis this season". Spokesman-Review. Spokane, Washington. Associated Press. March 14, 1960. p. 11.
- "St. Louis-bound Cardinals Chicago's oldest grid pros". Spokesman-Review. Spokane, Washington. Chicago Tribune press service. March 15, 1960. p. 11.