The 1922 United States Senate election in Montana took place on November 7, 1922. Incumbent United States Senator Henry L. Myers, who was first elected to the Senate in 1910, and was re-elected in 1916, declined to seek re-election. Former United States Attorney Burton K. Wheeler won the Democratic primary and advanced to the general election, where he faced Carl W. Riddick, the United States Congressman from Montana's 2nd congressional district and the Republican nominee. Ultimately, Wheeler defeated Riddick comfortably and won his first term in the Senate.
- Burton K. Wheeler, 1920 Democratic nominee for Governor of Montana, former United States Attorney for the District of Montana, former State Representative
- Tom Stout, former United States Congressman from Montana's at-large congressional district
- James F. O'Connor, former Speaker of the Montana House of Representatives
- Hugh R. Wells, former State Representative, former Chairman of the Montana Democratic Party
|Democratic||Burton K. Wheeler||20,914||54.66|
|Democratic||James F. O'Connor||6,296||16.46|
|Democratic||Hugh R. Wells||4,500||11.76|
- Carl W. Riddick, United States Congressman from Montana's 2nd congressional district
- Wellington D. Rankin, Attorney General of Montana
- Charles Nelson Pray, former United States Congressman from Montana's at-large congressional district, 1916 Republican nominee for the United States Senate
- J. W. Anderson
- J. C. F. Siegfriedt, mining company doctor
|Republican||Carl W. Riddick||23,334||33.15|
|Republican||Wellington D. Rankin||18,704||26.57|
|Republican||Charles Nelson Pray||11,911||16.92|
|Republican||J. W. Anderson||10,487||14.90|
|Republican||J. C. F. Siegfriedt||5,947||8.45|
|Democratic||Burton K. Wheeler||88,205||55.56%||4.50%|
|Republican||Carl W. Riddick||69,494||43.77%||+0.37%|
|Socialist||George H. Ambrose||1,068||0.67%||-4.87%|
- "Report of the Official Canvass of the Vote Cast at the Primary Election, Held in the State of Montana, August 29, 1922". Montana Secretary of State. Retrieved July 2, 2014.
- "Statistics of the Congressional Election of November 7, 1922" (PDF). Clerk of the United States House of Representatives. Retrieved July 2, 2014.