On December 15, 1815, having been elected to the Senate, Nathaniel Macon (DR) of North Carolina's 6th district resigned. To fill the vacancy left in North Carolina's representation for the 14th Congress, a special election was held on January 22, 1816.
|Weldon N. Edwards||Democratic-Republican||1,436||60.7%|
|William P. Little||||931||39.3%|
Edwards took his seat on February 7, 1816, during the First Session of the 14th Congress.
- List of special elections to the United States House of Representatives
- 1816 and 1817 United States House of Representatives elections
- List of United States Representatives from North Carolina