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|Ab urbe condita||2134|
|Balinese saka calendar||1302–1303|
|English Regnal year||4 Ric. 2 – 5 Ric. 2|
|Chinese calendar||庚申年 (Metal Monkey)|
4077 or 4017
— to —
辛酉年 (Metal Rooster)
4078 or 4018
|- Vikram Samvat||1437–1438|
|- Shaka Samvat||1302–1303|
|- Kali Yuga||4481–4482|
|Japanese calendar||Kōryaku 3 / Eitoku 1|
|Minguo calendar||531 before ROC|
|Thai solar calendar||1923–1924|
1507 or 1126 or 354
— to —
1508 or 1127 or 355
|Wikimedia Commons has media related to 1381.|
- March 14 – Chioggia concludes an alliance with Zadar and Trogir against Venice, which becomes changed in 1412 in Šibenik.
- June 12 – Peasants' Revolt: In England, rebels from Kent and Essex, led by Wat Tyler and Jack Straw, meet at Blackheath. There the rebels are encouraged by a sermon, by renegade priest John Ball.
- June 14 – Peasants' Revolt: Rebels destroy John of Gaunt's Savoy Palace and storm the Tower of London, killing the Archbishop of Canterbury and the Lord Chancellor. King Richard II of England meets the leaders of the revolt, and agrees to reforms such as fair rents, and the abolition of serfdom.
- June 15 – Peasants' Revolt: During further negotiations, Wat Tyler is murdered by the King's entourage. Noble forces subsequently overpower the rebel army. The rebel leaders are eventually captured and executed and Richard II revokes his concessions. The revolt is discussed in John Gower's Vox Clamantis and Froissart's Chronicles.
- August – Kęstutis overthrows his nephew, Jogaila, as Grand Duke of Lithuania. Jogaila is allowed to remain as governor of eastern Lithuania. This marks the beginning of the Lithuanian Civil War (1381–84).
Date not known
- Due to Joanna I of Naples' support for Antipope Clement VII, Pope Urban VI bestows Naples upon Charles of Durazzo. With the help of the Hungarians, Charles advances on Naples and captures Joanna.
- The Ming Dynasty of China annexes the areas of the old Kingdom of Dali, in what is now Yunnan and Guizhou provinces, inhabited by the Miao and Yao peoples. Hundreds of thousands of Chinese (including military colonists) will migrate there from the rest of China.
- James of Baux, the ruler of Taranto and the Latin Empire, claims the Principality of Achaea, after the imprisonment of Joanna I of Naples.
- Sonam Drakpa deposes Drakpa Changchub, as ruler of Tibet.
- Hajji I succeeds Alah-ad-Din Ali, as Mamluk Sultan of Egypt. The Egyptian government continues to be controlled by rebel leader Barquq.
- After a naval battle, Venice wins the three-year War of Chioggia against Genoa. The Genoans are permanently weakened by the conflict.
- Timur conquers east Persia, ending the rule of the Sarbadar dynasty.
- In Ming Dynasty China, the lijia census registration system begun in 1371 is now universally imposed, during the reign of the Hongwu Emperor. The census counts 59,873,305 people living in China in this year. This depicts a drastic drop in population since the Song Dynasty, which counted 100 million people at its height in the early 12th century. The historian Timothy Brook, in his The Confusions of Pleasure: Commerce and Culture in Ming China, states that the Ming census was inaccurate, as China in the late 14th century had at least 65,000,000 inhabitants, if not 75,000,000.
- October 13 – Thomas FitzAlan, 12th Earl of Arundel, English politician (d. 1415)
- date unknown
- March 24 – Catherine of Vadstena, Swedish saint (b. 1331 or 1332)
- May 15 – Eppelein von Gailingen, German robber baron
- June 14 – Simon Sudbury, Archbishop of Canterbury (murdered)
- June 15
- July 15 – John Ball, renegade priest (executed)
- December 2 – John of Ruysbroeck, Flemish mystic
- December 27 – Edmund Mortimer, 3rd Earl of March, English politician
- Brook, Timothy (1998). The Confusions of Pleasure: Commerce and Culture in Ming China. Berkeley: University of California Press. ISBN 978-0-520-22154-3
- "Saint Catherine of Sweden | Swedish saint". Encyclopedia Britannica. Retrieved March 18, 2019.